PREMARIN® (conjugated estrogens tablets, USP) Home Page | Safety Info

Premarin tablets are used after menopause to reduce moderate to severe hot flashes, treat menopausal changes in and around the vagina, and to help reduce the chances of developing osteoporosis (thin, weak bones).

If you use Premarin tablets only to treat your menopausal changes in and around your vagina, talk with your healthcare provider about whether a topical vaginal product would be better for you. If you use Premarin tablets only to prevent osteoporosis due to menopause, talk with your healthcare provider about whether a different treatment or medicine without estrogens might be better for you.

Menopause, Hot Flashes, and you

Keep track of your hot flashes and learn more about how they relate to menopause

Learn More about Hot Flashes

Savings Card Icon

IF ELIGIBLE, YOU CAN SAVE ON PREMARIN

Pay as little as $30 per month* for your Premarin prescription

*Terms and Conditions apply.

^*Terms and Conditions apply. This Card is not health insurance. This Card is only accepted at participating pharmacies. No membership fees are associated with this Card. Eligible patients will pay as little as $30 with a savings of up to $55 per prescription filled. Limit 12 offers per calendar year. Maximum savings of $660 per calendar year. If you are enrolled in a state or federally funded prescription insurance program, you may not use the savings card even if you elect to be processed as an uninsured (cash-paying) patient. Exp. 12/31/24. See below for full Terms and Conditions. For help processing, please call 1-855-477-7309. Pfizer: Attn: Premarin, 66 Hudson Boulevard East, New York, NY 10001-2192, www.pfizer.com.

IMPORTANT SAFETY INFORMATION AND INDICATION

Using estrogen alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using Premarin. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

Do not use estrogens with or without progestins to prevent heart disease, heart attacks, strokes, or dementia (decline in brain function).

Using estrogen alone may increase your chances of getting strokes or blood clots. Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

Using estrogens, with or without progestins, may increase your chance of getting dementia, based on a study of women 65 years of age or older.

Estrogens should be used at the lowest dose possible, only for as long as needed. You and your healthcare provider should talk regularly about whether you still need treatment.

Premarin should not be used if you have unusual vaginal bleeding, have, or had cancer, had a stroke or heart attack, have or had blood clots or liver problems, have a bleeding disorder, are allergic to any of its ingredients, or think you may be pregnant. In general, the addition of a progestin is recommended for women with a uterus to reduce the chance of getting cancer of the uterus.

If you take thyroid medication, consult your healthcare provider, as use of estrogens may change the amount needed.

Serious, but less common side effects include heart attack, stroke, blood clots, dementia, breast cancer, cancer of the lining of the uterus, cancer of the ovary, high blood pressure, high blood sugar, gallbladder disease, liver problems, enlargement of benign tumors of the uterus (fibroids), and severe allergic reactions.

Call your healthcare provider right away if you get any of the following warning signs or any other unusual symptoms that concern you: new breast lumps; unusual vaginal bleeding; changes in vision or speech; sudden new severe headaches; severe pains in your chest or legs with or without shortness of breath, weakness, and fatigue; swollen lips, tongue, and face.

Less serious, but common side effects include headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps/bloating, nausea and vomiting, hair loss, fluid retention, and vaginal yeast infection.

INDICATION

Premarin tablets are used after menopause to reduce moderate to severe hot flashes, treat menopausal changes in and around the vagina, and to help reduce the chances of developing osteoporosis (thin, weak bones).

If you use Premarin tablets only to treat your menopausal changes in and around your vagina, talk with your healthcare provider about whether a topical vaginal product would be better for you. If you use Premarin tablets only to prevent osteoporosis due to menopause, talk with your healthcare provider about whether a different treatment or medicine without estrogens might be better for you.

Please see full Prescribing Information, including BOXED WARNING and Patient Information.

Patients should always ask their doctors for medical advice about adverse events.

Using estrogen alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using Premarin. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

Do not use estrogens with or without progestins to prevent heart disease, heart attacks, strokes, or dementia (decline in brain function).

Using estrogen alone may increase your chances of getting strokes or blood clots. Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

Using estrogens, with or without progestins, may increase your chance of getting dementia, based on a study of women 65 years of age or older.

Estrogens should be used at the lowest dose possible, only for as long as needed. You and your healthcare provider should talk regularly about whether you still need treatment.

Premarin should not be used if you have unusual vaginal bleeding, have, or had cancer, had a stroke or heart attack, have or had blood clots or liver problems, have a bleeding disorder, are allergic to any of its ingredients, or think you may be pregnant. In general, the addition of a progestin is recommended for women with a uterus to reduce the chance of getting cancer of the uterus.

If you take thyroid medication, consult your healthcare provider, as use of estrogens may change the amount needed.

Serious, but less common side effects include heart attack, stroke, blood clots, dementia, breast cancer, cancer of the lining of the uterus, cancer of the ovary, high blood pressure, high blood sugar, gallbladder disease, liver problems, enlargement of benign tumors of the uterus (fibroids), and severe allergic reactions.

Call your healthcare provider right away if you get any of the following warning signs or any other unusual symptoms that concern you: new breast lumps; unusual vaginal bleeding; changes in vision or speech; sudden new severe headaches; severe pains in your chest or legs with or without shortness of breath, weakness, and fatigue; swollen lips, tongue, and face.

Less serious, but common side effects include headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps/bloating, nausea and vomiting, hair loss, fluid retention, and vaginal yeast infection.

INDICATION

Premarin tablets are used after menopause to reduce moderate to severe hot flashes, treat menopausal changes in and around the vagina, and to help reduce the chances of developing osteoporosis (thin, weak bones).

If you use Premarin tablets only to treat your menopausal changes in and around your vagina, talk with your healthcare provider about whether a topical vaginal product would be better for you. If you use Premarin tablets only to prevent osteoporosis due to menopause, talk with your healthcare provider about whether a different treatment or medicine without estrogens might be better for you.

Please see full Prescribing Information, including BOXED WARNING and Patient Information.

Patients should always ask their doctors for medical advice about adverse events.

You are encouraged to report adverse events related to Pfizer products by calling 1-800-438-1985 (US only). If you prefer, you may contact the US Food and Drug Administration (FDA) directly. Visit http://www.fda.gov/MedWatch or call 1-800-FDA-1088.

Doctors may recommend alternative treatment options to their patients.

^*TERMS AND CONDITIONS

By using this Premarin Co-pay Card, you acknowledge that you currently meet the eligibility criteria and will comply with the Terms and Conditions described below:

Patients are not eligible to use this Card if they are enrolled in a state or federally funded insurance program, including but not limited to Medicare, Medicaid, TRICARE, Veteran Affairs health care, a state prescription drug assistance program, or the Government Health Insurance Plan available in Puerto Rico (formerly known as "La Reforma de Salud").
Patient must have private insurance. Offer is not valid for cash-paying patients. The value of this co-pay card is limited to $55 per use or the amount of your co-pay, whichever is less.
This co-pay card is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plan or other private health or pharmacy benefit programs.
You must deduct the value of this co-pay card from any reimbursement request submitted to your private insurance plan, either directly by you or on your behalf.
Eligible patients will pay a minimum of $30 with a savings of up to $55 per prescription fill. Limit 12 offers per calendar year.
- If your out-of-pocket cost is $85 or less, you will pay $30 and save up to $55.
- If your out-of-pocket cost is more than $85, you will save up to $55 with this co-pay card and you must cover the remaining expenses.
Maximum savings of $660 per calendar year.
You are responsible for reporting use of the co-pay card to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using the co-pay card, as may be required. You should not use the co-pay card if your insurer or health plan prohibits use of manufacturer co-pay cards.
You must be 18 years of age or older to redeem the co-pay card.
This co-pay card is not valid where prohibited by law.
Co-pay card cannot be combined with any other savings, free trial or similar offer for the specified prescription.
Co-pay card will be accepted only at participating pharmacies.
If your pharmacy does not participate, you may be able to submit a request for a rebate in connection with this offer.
This co-pay card is not health insurance.
Offer good only in the U.S. and Puerto Rico.
Co-pay card is limited to 1 per person during this offering period and is not transferable.
A co-pay card may not be redeemed more than once per month per patient.
No other purchase is necessary.
Data related to your redemption of the co-pay card may be collected, analyzed, and shared with Pfizer, for market research and other purposes related to assessing Pfizer's programs. Data shared with Pfizer will be aggregated and de-identified; it will be combined with data related to other co-pay card redemptions and will not identify you.
Pfizer reserves the right to rescind, revoke or amend this offer without notice.
Offer expires 12/31/2024.

For reimbursement when using a nonparticipating pharmacy/mail order:

Pay for Premarin prescription and mail copy of original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: Pfizer, Attn: Claims Processing Department, IQVIA, Inc., 77 Corporate Drive, Bridgewater, NJ 08807. Be sure to include a copy of the front of your co-pay card, your name, and mailing address.

For help with the Premarin Co-pay Card, call 1-866-410-3700.

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